European Respiratory Society Annual Congress 2013
European Respiratory Society Annual Congress 2013 Abstract Number: 7008 Publication Number: P4970 Abstract Group: 2.2. Noninvasive Ventilatory Support Keyword 1: Mechanical ventilation Keyword 2: Ventilation/NIV Keyword 3: No keyword Title: Long term use of nasal high-flow in COPD Dr. Jens 53 Bräunlich [email protected] MD 1, Dr. Hans-Jürgen 54 Seyfarth [email protected] MD 1, Prof. Stefan 55 Hammerschmidt [email protected] MD 1 and Prof. Dr Hubert 56 Wirtz [email protected] MD 1. 1 Pneumology, University of Leipzig, Leipzig, Germany . Body: Introduction: In the last years nasal high-flow was described as a new tool to treat patients with acute respiratory failure. The effects vary from a better oxygenation, a decrease in breathing rate and dyspnoea scores. At this juncture there exist no data about the application in adult patients with chronic respiratory failure. Method: In this observational prospective study we included patients with COPD, hypercapnia and no exacerbation six weeks before enrollment (n=9). All patients had a complete medication and long-term oxygen therapy. After enrollment the patients completed a blood gas analysis. They received a nasal high-flow device for six weeks. After them, the analysis was repeated. Results: After six weeks, the patients showed a significant decrease in pCO2. The nHF device was well tolerated. Discussion: Nasal high-flow is able to improve symptoms of respiratory distress. A decrease in breathing rates and in minute volumes indicates a reduction in breathing related work. The main parameter of the efficiency is the reduction in hypercapnia. For this reason nHF could be a powerful tool in the therapy of chronic respiratory failure.