...

auiM

by user

on
Category: Documents
4

views

Report

Comments

Description

Transcript

auiM
UNIVERSITY OF CALICUT
ract)
emester) of affiliated colleges under credit
s-PG-2010) implemented with effect from
GENERAL & ACADEMIC BRA
No. GA IYIJI/4279fi0
U.o.No. GAIV tI t I 137 3 tor
_
!ut.d, Calicut University
auiM
PO, 26.07 .2010
Minutes of the meeting of the Board of Studies in Zoology (pG)
of
09.06.2010, Item No.
3' orders of the vice-chancelror, in the file of even number
dated29.06.2010.
4. Item No.III a.30 of the minutes of the meeting of the
Academic council, held
on 03.07.2010.
As per reference cited 1r; uoor"ffi.rnester system post
at
Graduate lever
in affiliated colleges(cucss pG-2010) has been implemented
from the u.ua.,ni. y.".
2010, onwards.
The Board ofStudies at its
cited (2) above, discussed the
scheme and syllabus of pG
s and has forwarded the
scheme and syllabus of Ist Semester
mee
(Zoology)
The Vice-chancelor, in view of exigency, has approved the
minutes of the
meeting of the Board, subject to ratification Uy ttre acuae-ic
Council.
The Academic council, vide paper read as 4'h above,
ratified the action of the
vice chancellor in having approved the mir utes of the meeting ortir"
noarJof studies
in Zoology.
Sanction has therefore.been accorded to implement the scheme
and syllabus of
MSc Zoology of affiliated colleges under Credit S'emester System
with effect from 2010
admission.
Orders are issued accordingly. Scheme and syllabus appended.
sd/EGISTRAR
TO
^
1. The Principals of all affrliated Colleges offering M.Sc Zoology
2. Self financing centres of the University of Calilut offering ZilfogyeC;
Copy to:
VC/PA to Registrar/cE/Digital wing_(with a request to uproad
in the Univenity
website/Enquiry/tnformation centrevoR'ili gxams/EGJIDR
igr"uri"r"Jceii;r .e,
Section s/GAII/GAIII/DDLFA/SF/FC
PS.to.
tt
,\
a
[+eer*o
r
r
To
15'o? .lo
oo e,aQ lo' lrea I ro
I
tD
('IrRi.]i('t;l i;N1 '\ND Syt-lri:l troR
14.\c ,/t t( )i r lt-iY (- ortl-se utrcier
('iroigi, I3itscrl ('retlit Setlrestt':i' Svstem
rt'(
S S)
FIRST SEVIF,STtit{
Theory Courses
(
ocle No. cQ
'l'itle ol'thc (.ottrsc
ZO-l('-f 0l- Biochenristr) -7i---f;r-R;.pn, *.i -d
; Brostatistics
-t.O tCS -() j - S,v- stcrlr at i c s and
Evolutiotr '
(
rcdits
Ex te
rnal
1
ry1r:ls
15
1
15
lnternal I 1'otal
marl<s
I
25 i 100
25 ,;lil ifltt
,l100
---+-
4
15
?s i
i
I
I
I
|
i
I
Iota
l)t'ltettcal
C
15 I
i0(i
rrLll'SC\
I Ct,de No. & .l'itle ol'the Cotrrse
S\ stellltltlcs
I
,/( ) - l.oolttgr
i - l;,c;11cr1ct
t l -(rrttls! lllerrlr
( l) - ( rrrrrSC i)riteltCltl
I
r.'-
J'HEOII.\'
7
ZO-I
C
1--0I
a
. BIOCHEMISTIIY
(
90 ho Ltrs )
Iinit - I - ('hemistr.r, antl l'unctiuns 0f Bi0m0lccttlcs
l.
(2 hrt
lntroduction
. I\4acrott-tolecLrles trncl thcir sttt-rlttlits
I.1. C lrcnrical btlrrds of hionl()lcctrlcs
I.I
2.
rl2 hri
Carbohvtlrates
l. I . Monosaccharicles
. Classiticatior"r
with erattlrples
2.1.2. Structure of glucose. fiuctose. galactctse. n-lannose and ribose
2.1 .3. Methods of- repleserltation o1 sr-rgars (Ball ancl stick. projectiott tormula
2.1.1
and
perspecti ve fbrmr"r I a)
2.1
.4. Isorrrerisrrr Structr-rlal isclnrerisnr (l'r,rrrctional groLIp isOtr-tct'isnl ) and stcleo
isrirlcrisrr-r (gptical i ouicrisnt)- rrrcntiorr c1-litlcr. Llnottltl' atrci ctlatltitlnrct' 'uiith
cxamples
II-i
urtarotatiott
6
Reactions Oxiclation (bl acicls. rnetal hr,'clroxitles
.1.
acid) and redr.rctic-rn (bv alkali). reactions with alanine antl pitenr'l il1'drazinc
Derir,atir,,es ascorbic acicl. arcctal ancl [rcrliacctal. ketal atlcl ht:tltiltctalgly,,cocosides - s[_r,cosiclic boncl anri rlcoxr ribosc
).1
2.1
N4
2. I .tt.
tliologicitl t'olcs ol'tlrolrt)Sile
2.2. Disacctrarides
2.2.1. Structurre ancl l-liologicarl
Chrtt'i.le
artcl H1O1 t. deh,vclratiorr (h)'
:
r'..rIes o1'Nlalto-sc. SLtcrosc.
Lactosc. ('cllobiOse atld
T'retialose
2.2.2. Biosvnthesis of trehalose and lactose
2.3. Poly'saccharides
2.3.I . [{6rlptrlr,,sacclraridr.s Structure und brological I'oles ot' cellLrlosegl)'coger-r. intrlin and chitirl
sLarrch-
2.3.2. Mode ot'action ot'anrvlase on honropiiIvsacchar.icles.(starch ancl gll'ctlgeri
2.3.3. Heteropolvsaccharirle - Structurc ancl biological roles ot' h,'-aluronic acici)
chorrdroitin. cIgnclroitin suIphate. l..crataur sr-rl;lhate. heparit-t
-)
iltrcJ aqal'-agar
11)
Proteins
hr)
3.1. Auriuo i.rcicls
3.1.1. ( lassification: (a) urr the basis of'r-rurrber of'amino
hasrs
and carboxvl gl'oLrp (h) orl thc
of the chernicirl conrposition ot'sicle chain (c)based on tlie polaritl ot'sicie
chairr (I(
)
.1. Amphoteric pl'()pcrtics tl1';-ttltirltr lre rtls
3.1 .i. l)A' r alrre ancl isoclee t:'ie ltoirtt (pl) ol';.ttt.tit.lo ltuitls
3. I
3.1
.,1. lreptitle bontl rulri pc1-ltitle s (tli. tri. tctt'ir. oliSo itlltl lltrlr llcPtrttg
i
3.2. StructLrre of' proteirr
3.2.1
.
l)r.it-lt3l.\ strurctr-rr.e. Sct.\)pclzy'\ stl'1ctu;c (g-hclir parallcl ct .ltttiparalle-l ancl
'['crliarv strltctttrc. ()ttarterttarr"
pleaterl sheet). randonr cttil coutirrrlrirtitlr-r.
[,t
structurc.
')
3.2.?. BLiet'ntlre on pnrtcirr tlontains.
nrotit.s. firlds arrd I{attrachattclratt 1llot.
3.2.-1. Lliological t'ttlcs ol' 1'rrotcitrs
(8 hr)
Lipids
I I. ('lassillcatign ol'lipitls -Sintplc lipitls (fhts. oils and \!itxes). cott-t1-roittrcl lipids
(phospholipiris. slr ctrlipitls. lipopnrteitts ztttcl sttlpholipicls) antl tlet'ivecl lrpitls.
+.1. il;icl acc()Llllt o1'thc chcnristrr ol'stct'ols. tcrpclles itllcl cartltctloitls
I
1.3..\cicl nirrltrcr'. sap()nillcirtion
nr,rnrbcr'. Ioclinc nt-tttrtrer.
I'olettslie ntttlttret' and Reichert-
\4eissl nitnit-ret' o f' lipids
lirocl rcser'\es (st()t'agrr liltids). stl'LlctLrral li;:icls irl
rlertrt-rranc. as signals. as co-titctol's. as pigments. as instrlators. as vitattTin carriers etc
+.4. lliolosical
rolcs
ol'liPrrls ls
1.5. l)r'pstaslarrclitrs ('hctttical rlttLrt'c tLtld f ttlrctlolls.
1.6. l:attl acids - detlrtil.iott. cssclltial tirttt' acic]s
. Classiticatiop u,itlr er4r'nples Saturzrtecl. unsatluratecl.
4.8. Ntltrettclzrtltre tl1'llrttr itciCis ( icttcr an SVStelrl
1.1
5
N
hi,dt'oxr,'l ittltl
crclic t'att1'acids
(5 hrt
ucleic :tcitls
5. I
.
Str-Lrctrrt'e
of'nitt't-luctr bitse s tttlcl tlttcltltrticle
s
5.2. Strr,tctural orgartization o1'DNA 1\L'atsot-l :Cricl< nlodel)
5.3. Characteristic leatr-tres o1'A-. tl- ('- and Z-DN,A
5.4. Structural organization rif t-t{NA: brief nclte otl tllicro-RNA
5.5. fliolosie al rolcs ol'nuclt:oticics itttcl rtLrcleic acids
tl5hrt
I nit
('lassitlclrtiorl- ( I t i. t]. s\ stclrl
Speci
-+
trcitr
)
ot' ettz-r'ttte i.tcti()ll
(iibbs l.t'ee eneIgl 0l
Mechirpisrp pl'c11.\iltc Lrctitlrr: lirit'ptirtittp rlf'enzvnte sr-tt-rstrlltc cotllplcrlcti\irtisrr: \'lichaelis-Nlcntcn tlrcorr. lrischcr's tcntplate thcor'1'arld K,rshlarlcl's iliclLrcecl flt
theorr. I:lccrrostlrl.ic. hr,tll'()gcl't itrrtl \/an clcr Waal's btttlcls irl lirlzr,trrs-sLll-rstt'ate conrtr-llex.
F:1zvl1c [..ilctics l lVlichaclis-i\4clrtelr cclLratiott ciet'ii,ettitltt: signillcallCc'of K,,, tlnLl V,,,,,,,
Values.
)
6
Liner,vezii er-[]Ll;l\ ecprtttion antl clouble reciprocal plot o1'ettz-vt'tle
t'e
Llctitrtl
Enzv;1e iphibitiop - Cornpetitive. non-collpetitive and utrcompetitive irrhibitrcln (clistittgutslt
kineticallr,). suicide inhibition and f-eedback inhibition
Allosteric eltZvtttes ;ltlsitii'e ittltl tleglttir e lllOdulators
1.
B. Istt-ettzr"ttte attcl ritrtlzltrte
9 Vitarnins as c()rlcltz\ lttcs
l() F:itcti'lt's irtlltreltcitt" ctl/\ ll'ic lte liot't
Irnit - III- l]iocrtcrgctics
(5 hri
. lttltl bitllocie itl :,t stelll. L.rlthalp" ' L:titropt [rrcc e rlt: rg\
I ne rur trl'lrctir irtittrl. \t:itltiitl'tl lt'e c cllcl'g\ charlge
Ilole trt' \ ll) as a ticc cncr'!\ cltt'rict'itr thc [-rloltluteal :"stcll-l
l.zrws rrl titct'tttttclr tlitt'ttie
L)ottccpt
I
nit - I\'
-
,
Metah0lisnr ancl birtsYntltesis of biolnolccules
nretabolisttl
I l. clyc.lrsis (pFK as paccnralicr' []erol<irrasc conlirnt.tatiotl
('at'bohridratc
, ,
ancl clrange
tl5 hrt
b1 glltcose)'
Fate of P\/rLlvic acicl
oxvsen transport
1.2. Metabolisnr of 2. 3 DPG as regulator of
atrd ketogltttarate cleh,vcil'ogenase
1.3. citric acid cycle: pyruvate ctehydrogellase complex
cotrtlllcr
1.4.
I
.
j.
I{edox porcrltial'
Electr.. trarspor-t 5r,s1g111 anrl oriciirtive plroslthorl'lattiotr:
lrallsl--l0t't cltl'ritl
C'Se.ri.srrotic hr,1'rothesis: inhihitrlrs ol'clcctt'0tl
svllthesis
cil),cogencsis. Gl1,'cogenolr sis: t'egLlltttitltl o1'gl\c()sell
atrd
Cjluconeosenesis.
breakdou'rr
1.6. Pentosel'rhosphate pathwa\ (l IN{P pathvi'ttr
)
. Atlltt0 acid rnetabolisnr
l.l . Biosy ntlicsis arrcl cleg;atlatigtt ()l'attritlp acitls
rnethirtnine. try'ptophan. isolcttcine. histiclirre
'
. Lipicl ntetabolisrrr
.
l.l.
i.i.
3. I
(5hr)
gltttlttttie acicl- ;lhcnr I ltlittritrc'
.
([J
hrt
Oxidatiott o1- tattr acicl '
Lliosvnthesis ol' filttl acicls
Biosi ntltcsis tlt' cholestcrol
(6 hr)
Nucleic acid nretabolisrtl
4'1'Biosynthesisarrcldegractatiorrolptrrinesettrdpvranliclines
lleferences:
c BS prrblishers
I L,enhninser.. A.1.. (200g). pr.incipies of Biochemistrr. v'l' editiorr-
l.
tli stril*-rr-rtot's- [ )e
I
h
arncl
i
K. \4urt'ur^ [)ttt'r I t(' tit'atrtlcr- Petcr
l-larpcr-s []i.chcrrristr.,. 1lr)t)(r) l+'r' I':dition. Ilobcrt
I)t'ctlticc lrall ol lntlia l)t'irttte
A. Ma\es a.cl Vict.r s. [{otlu,ell:,r\pplct()rr r.urd l.ungclimited. New Delhr.
''.1{. lit'ectlrzitl & ('o' \Y
j. Lubert Sta'cr.-( .
) Biochentistrv. ll ctlitiort. \
(it'ai'r Ilill I]ool'' ('o'
4. oser. F].1. . ( l965) Ilar,r,k's Physiologictrl tliochctrtrstrr. N4c
t()utlitles o['
5. l_.ric t ('qn.. l)i.rul K Stunrpr'. (icorge IJrucning. l{or ll I)oi- t"'
(l(X)7 i'
Bi,chc,ristr'-r . \,"1' erlitittrt. .ltllttt Wiler & Sotrs- lllc'
('Er-rtItrJ []oolt ''\sctte r (1'}) Lttl'
6. Deh. A.('.(2004) FrrncliinrentLtls ot'hiochcnristrr - Ner,i
7. Keith \A,,ilsor-t arrcl .lohn \\iall..cr.(200ti) Principlcs uncl teclrnirlltes ol'Ilioehcttristt'r'rtttd
('ltttrbriclgc [:ttir e t'sitr l't'css
M.lercr-rlar biologr, (t'l' ctitt.
l.
g. V.et. l). a'cl V6et..l (i. (l()()4). lliochentistr\..lolitr \\'ilcr & Sotl'
Itttcrttatiottzrl
). tlioclrenrrstrr. Marucll \lacniillarl
9 1.urbar. C (
10. Der,lirr.-l-.M. t2906).
Sons
W'ilcv &
A'['ext 9l'Bioclrcnristrr,riith clinical con'clzi'tit-rtrs-.lohtr
ZO-I CT.O2-BIOPHYSICS AND BTOSTATISTICS
(90 Hours)
t55 llours)
Section-A- Bi op hy'sics
3 hr
l- Matter and mechanics ol'cells
I
--( oIloids. pr()perties ot' ct'rI Ioicls. lirrnrs ot' coIloicis.
Brttwttian tttovelttellt attcl
-[r'tlclaI
I pItentltrlella
5hr
2- Diffusion and Osmosis
l.l- - Fick's lar,v and clitftrsion cocll tcicrtt.
2.1- Gibb's [)onnan ecl-ri I i lrriurl
2.4- Application of cliffr-rsit'rn proccsses in biologv: haemolysis.
2.5 -Vant Hoff.s laws
2.6-Osrnotic concentration. Osrnotic pressure and osmotic gradient
2.7- Electrosnrosis.
2.8 -L.lectrolvtic and ionic [-ralatrcc in bioloLlical fluid
2hr
3 -Pr-r
-1.
I
. I)issociatiott of water
I.1. I)iss()ciation ol'a wc:ali acicJ
i.i.
Henclersotr I-{asselbalch eclltatiotl
3.4; Buffers. pH nteter
3.5.
4
-
pl-t value calctrlation.
5hr
Bioacoustics
4. I -C'haracteristics
4.2-Physical basis
of sound
o1'
hearing
4.3-Physical organization of ear
4.4- Phvsical aspects t-rf souncl trilt'tst.ttissiott in the ear.
4. 5-A r-rcli ble
sottttcl fi'eqtretrcv
4.6-Pitch rcccptiott iutd thcorics
4.1 -lttfi'etsonic attcl Ltltrasotlic stltttrcls
4.tt EchoIttcati()lt: l'CCei'' inu rttlcl itllalr,z-irls cchoes
thr
5 -Radiation Biolog)'
5.1
-. Propc-r-tics ol'clitterent t\ pcs o1'r'arlio isotopes nonTlallv
r"rsed
in Lrioltlst'- thcir dctcctiotl
rneasLlreprenr ipcorptlratiorr o1'rac'liois()t()pes in biological tissues aud cells.
5.2- lr4olecurlar intagiltg o1'r'aclioactivc tlittcrit'rl. safetl' gr-ridelitles.
5.i-Biological
c'tJ'ects clf radiatiotrs
5.4- Racliation plotection attd therapr'. Nuclear medicine.
ancl
isotoPcs' lotrizing
5.5-Applications ol'tracer' lechrriqucs: Itadiatittn dosintctt'r. I{adroactivc
('tluutel')
radiatio's. I{acliation [)etcctr)l's ((ilvl ('or-rnter. [-irlLrici Scirrti[[atiotr
5
.6- Autoracl iogritPh
i
tliophysical methocls (Rrief
6-
5 hr
account)
dichl'oistlr
6.1-Anatysis of bicln-rolecules-using LiV , r,isiblc llr"rorcsccllce. cit'cular
6.2- NMR ancJ Irlectron Spirr ResgrlLlrrce (l--SR) sllcctt'.scoll\
6.3- St*rctur.e ciet,erntirratiop usip., X-r'al dil'fl'action lutd Nlrll{- ar-ralvsis
r,rsi
rtg I ight scattet'ittg.
nlethtltls
6.4-Different types of rllass spectl'otlieLl'\ ancl surlitcc plasttla rcsonallce
7- Electrophl'siological
7. I -Single
3hr
methods (Briet)
neuron recording'
7.2-patch clamP recording7.3-ECC].
7.4-Brailt itctir
itr
rccording
7.5 [-esion attd stintr-rlation o1'brain
7,
6-Pharnraco
Io gi
cal testing-
'fontographv). MRl. I MRI. (',A'l'.
l.l-PE'T (Positlop Flmission
tl hr'
8 -Principles and applications ol'
g l-N4icr()se 0;lr (l lLt()l.csccl.lt. lntct'le [cr.tcc
- e()nlrre
lrl
-se
itlitlitlu i.ll]rl Il'itl)\l]ll\\l()ll
eieutt'trl't
nllc rosc()pcs
8.2-Resolving powers of dilferent nlicl'o5c1rp€s
g.3-Dif1'erenr t-lxat!<-r6 atrd stainirrg technicltres tor F.M. (ll'eeze-etch anci lreeze fractltt'e ntethclds
tbr EM-itnase prc'rcessing urethods in tlricroscopr,r
)
8.4- l-arser ancl its applications irl I]iology
9 - Separation
9.l-
'I'echniques
ll) hr
Paper
Chrornatograph,v (Adsorption. Pat'tition. ancl ion-cxchr,-tg. chromatographr'-Colr-rrnn.
.Thin-layer -(iel-llltratiun. (ias chronratographr'. ,Afllnitr. lll't.(')
-l'wo
clitnensit-rnal P.\GIr. High voltasc
9.2-Electrophoresrs-(Paper. I)isc- I'AG[:..
alrcl
Inrnr Lrnoc Iectr-ophttt'es is.
9 3. Isoelectric lircursing.
9.4-Flou c\ t()ntetl'r
3 hr
1
0. I ntluence tlf grav itr
I
0.I -l-lr-rrnatr l-rociv pt-rstttre irr tl're grar;iiational t'ielcl
l0.l1
().l-
lntltrcttcc ol'( i lirrcc
Irorce of'cetrtrifirgal acceleri,rtic-rt-t - intpclrtance rlf aviation and Space tt'avel
I0.4- llttect o1'positive
(1. frorce
& negative (i. l'orces
- l)r'otce irorr against ( i.
l:'rircc
6- Inlluencc tll'linear- Ltcccleration orr thc bodv
2hr
Nanotechnolgr
l.l- Dellnition
I l.l- Nltnolce hnologr rrrrrl its ap1-rlicutrons in tlte llelcl t'r1' hcalth care.
I Ll- [{oie s ()l nar]()tccltrtolosr in crrr iror.tntcntttl l-nanaqcnrent.
I
Section
I
-B -BIOSTA'l'lS'l'l
( 35 Hours)
CS
2hr
. Introductiorr
I I Ilio:ttr1i:tics [)t'llnitiuti. It'llr:.'\ltpliclttitttrs. Iiolc ol' [riostrtistics in
t'cse rrrc
li.
7hr
2. l)ata collectiorr:
.
n'tot]crt.t
l. I l'r pes o1'rllrtzt:
- Prir-rrarr. scctlnrlar'\ -
l.'l
rluaIitativc. quantitative
\,'lethocls ol' riata eoI lcction
ar
irl cIiissiflcation.-
l't'pes ol sant;llins tnethodAdvantages and disadvarrtages of census and santpling lletlrod.
ffi,"l:iil::I",;l ,bua"n
('lass intervals- erclusive itnci inclusive nrethocj
2.3 Diagrantnratic and graphicltl plcsetttatiott of datil
[]ur tliagrant (t1 pcs ). l'}ic diagrarr. Flistogrartns. [rrcclLrcrlc\ polr gtttt
lrt'crlLreltc\ cLll'\ c (t-r 1'lcs.
sl<cr'r
ltess. kttt'tosis. ogir.'c
3. Statistical Methods: McirsLrrcs t.rt'ccntnrl tettdencl artd
)
clispersal
i.I. \4ean. Ilctliettt. tttotle. tltrat'tilc
l.l I{angc. Nlcart tlcr iutiott. Qrrartilcs cleviatitltl. r ariancc. Starrrlitt'cl .lcviati,t,t.
8 hr
Sianclartl
elr()l'. dcgrec ttI fl'cecltlnt
-1.
4hr
Proba bi lit-"" d istributions
.1.I. Basic concel'rts ancl tlelirtiliott:
+.1. I .a\\ s o l' 1'lt'ttt'xtbi l itr
4.-1. Probabi
l
itv clistribtrtiott:
Binontial. Poissotr
ztttcl
-
\ot'tllal
7 lrr
5. Statistical inference
5.1. I)illcrcnce hctrrccn pLll'errctric
,r.1. I cstins ()t'ltr pothcsis
5..1.
I
t-t't)r'S
r-trtcl
rlon-parantett'ic statistics:
5.4. ('unflc[encc intervzrl. lcr,cis ol sisrtiiicuner'. t'r'itical rcuion:
5
_5.
\orrlalitv
test
5.6 l-tcst. chi-sqLlarc
-i
7
.
6l.
,\NO\ \
Knrskrrl-\\ allis. \,lluul-\\ iritrrcr
(t ('orrelittiort
(r.l
Lest. lrj-tcst.
rrncl llcgl'cssiolr
l-r i-rcs
7 hr'
rrl'c(rrrclution
\'lethtrtls to n'tcttsure c(rrrelation
Scattcr cliagranr
lr.ltt'lpcltrs()n s cocl'llcicnt ol' corrclatiorr
S
peanniln
-\ e()r'r'cl lrl iurr
6.I I j 1..'- ()l I'CSt'Cssirrp .lplllr .,rs
6
I
6.
-5
I(u.r:r'cssitrtl cr[tuttiort:
.
l)i
ll er-ertt:e helu'er't't I'crjrc:S i on r-tnti c()r't'c l itt i t rrr anlr l r s i s
REF'ERENC'ES _
tsIOPHYSICS
1. Ackerman. E. ( lL)62).Biophysical Science. Prentice Hall lnc.
2. Alonso. A
erttcl
Arrondo..l,l- tl (2006) - Ad'n'arrcecl techniclues in Biophvsics. Springer
l. Albk Srir,'astar,'a
arncl
lpsita Ilor'-(2009)-Bio-Naltc)- (jeo Scienccs-'l'l'le l'uture cliallerrge-Ane
Books [.tcl.
4
Bakcl'. t,..1 lrtcl Srlvel'tttn. t{.E. (197t{l
-5.
Bengt Nolting ( 2006). IVlctlrods irr nroclcrn []iophr,sics. Sprirrgo'.
-
tttlruclr-rction to ntcdical laborattlri teehnologr. L.l.l}S
6. [)aniel. l\4 (](X)2). Basic Biophrsics firr Biologists.,\sro []otarrics. Bil<arrer'
7. Das. D. tl()t)l)[]ioph1,'stcs arrcl []io1-"'[l,sicll
('hcrnrstri. telrtlcrnic I)rrhlrsltcrs ('alcutttr.
tl. L,nrster. [- t lL)ti5 ). lJioencrgetics. [:lscvicr-. Ncu Yor.k
9.
Frank H. Stephenson (2006)- ('ulculatiorrs lbr l\4olecularr llioloqr ancl [Jiotcchnolog) -
A guide to Vlathematics irt the laborettory-Acaclenric Prcss- An iurprint of'b.lscrier.
10. Hoppe. W. [.ohmann.W.
Markl.Il and Ziegler'.H (1983).springer Verlag.Ncu,york.
I1. Keith Wilson and .[t'rhn W'all<er (2008). Principles ancj techniqr_res of' l]iocheuristrv
Molecular biologr 6'l' ecln. Curnl'rririgc [ ]rrir crsitr I)rcss
ll.
Vlarshall- ,\.(i. (l()7t{) I}iopltrsie;ri t'hcrnistrr. I'r'ine rltlcs. Icclrrriclrcs lntl ,.\pplications-
.lohn
\\iiler
nrrcl Sons Nevr,Yorl<
l.i. Mohan P. z\rorat-(2001). Biophvsics
14. Mr-u'alirllr;,rmr-r
.Arte Booi',s
l-). \at'a\lllt.
\'.S.
-FIintala-r rr l)utrlishirrg IloLlse
anci Srrbrurntirrriu.,\
(l0l0t-
.
\rutoscicnee uncl Iccltrroltrur-
I ld
I'}
tl(XX)) [:sscnlials t,i liioplrr
sie
s \e ri lrlc intcl.nalioriai
16. Nagini.S t200t))- Insturtt Biochcntistl'r-,,\nc llooli: i ltt.
aud
ll.
Ro)'. R Nt 199(r)-A text ['rool,. of'[-]iophvsics-Neu central bool< Agenc_r ('alcr,rtta.
18. St'ivastat a. P.K (2006)-l-.lerncntarv ISioplrvsics.
Neu, Dellr
An introcluctit'rn. Narosa purblislrin-u
hguse
i
lc) Viswattathan. t)(2()09 )-Nant, lvlaterials- Narosa Publishing
IOS'I'AT'I S1'I CS
l. ,\sarii,al. I].1 . t l()96) llusic slirtisties.
[-louse.
B
L tlailcr. \ l..f
3. ('antpell. I{
C (l97ti). Statistics lbr biologists. Blacl..erand
Rostogi.\'
6. Steplrcrr
V (2002)Statistical
Sons Publishers. 13ombay.
nrethocis. il<as Publishing I-louse. New,Delhi.
l.l. (200c)) [runclanrentnls o1'[]iostatistics. Ane's Students L.clition Neu,Delhi
\\/.1 .ooner (2t)0ti
InternntionaI
1
.,\gc Intcr-nutional(lr) Ltcl. prrblrshcr-s. Ncir I)elhi.
(l(/l'i I ) Stirtistieirl rnctlro.ls in []iologi. Ilodcler arrd Storrslton. [.ondon.
4. (iupta. C Il. ancl Gupta.
-5.
\cri
b.cl
)
Nlethticls irr Nlolecular- Biology-Biostatistical Methods- Springer.
itiorr
Zar. .l.tl.tl003) [Jiostatistiizrl ,-\nalvsis - [ ourth eclition. Pearst'rn l:clr-rcuti,,,r. I)elhi.
ZO-I CT-03 - SY'STAMATICS AND E,VOLUTION
(90 hou rs)
Section A. Svstematics (45 hours)
l. Definition
I
I.I
,lfl r
and basic conccpts in S,vstamatics and Taxonomy
Iistoriclrl rcsrnlt: ol' sr stlrrrratic:
l.cr cl: ot' l-lrtorrtln.tr
,{lplra. beta. uanlla ta\()n()t.lt\
I
.2 PIacc. inttr'lt-lrtiutce
1..1
an<.1
a1t;lIications of'tatononrr
Goals ot- tarc)n()t"n\'
2. Classification
2.
I
4FIr
Prtictise ot' cl,rssiflcation- pLu'[l()sc
l.l
o1'
clarssilication
t isc ol'classitlcatiorr- storaSC of 11ata. reco\,er-\ of rlatir
2.i'l-heories
o f'
hiological cIassi trcation- [iierarchy ot' categories
2.4 Types of classiflcation--er,'olutit-rnarr, & phy'Ioger-retic classificatior-r typological
classiflcation. pltorretic classilication. onmispec:tive classiflcation. horizontal and rzertical
classitlcittion
l.-i ('rtnr[)()ncnts oI' cIltssi
3. Taxononric
i.I
.
I
rcaLiorr
procedurc
'I'ar()nontic
8 [-lr
collections- t\ l)cs ol'collections. r'alue ol'collectiorrs
3.2.. ('r-u'ittion- preservatirln trf'collection in flelcl and labot'atorv
-1.i. Rccot'rlittg of'llcld tlatu. st()r'u-!c ol'collection. lahcllins urrcl ctrtlrlourrinq ol collections
i.4. Iclentiflcation-
ntcthocis ot' iricnti llcatiorr
I 4 l. I
t''i'[ic]s- liincls rtl'kci s. tircir ntel'its ln.l
se
i.-;. I a\r)llr)rltic
3.6. Kinds
de
nrcrrts
t
descriptiorts: Prcscntatiorr ol' linc[ings
taxt)t'lontic publ icatiorrs
o1'
3.6.1, Taxonomic atrd ecological publication ancl their cli1'[L:rence
.1.
7 llr
Species concepts
'+.1. Specics categorl-- clil'l'erent species corrcepts: tvpt'rlosictrl. Norlinitlistic.
[-riolo-uical.
evt-lltttittttal'r. l'ec()sltition. orttoliruical ltheorctre al) arrrl opelaticlnel ic;listerlological
concepts
li
intls ol' specie':;.
sLr[^r
species and othcr'
tic categories. hvlrrids.
spec.i
5. Taxonomic characters
5.
cics
)
4.2. ['aront-rnric cliversitv w,ith in species. clifltrent
intia
spe
J
I diff'erent kinds of'taxonot.nic
IIr
characters
-i.l Futrctions ol' tarorrornic chlrrlr.'tcrs.
5.-l taxonorrric charactcrs
trr-rti classi I rcirtton
5.4 Taxorrornic characters aud evolutiorr
6. Zoological nomenclature
5 Hr
6.1 International Code of' Zoolo-uical Norlenclatrrre. development ol' ('ocle of
Nomenclatttre: its operative principles. irrterprctatiorr and applicatiun
tiirnration
6.I
Pri nc
i
o1'
p
scientilic narncs ol' r,arior.rs
le
o
l' priori
o
'1.o<t
logical
l' inrportunt rules
in
the
Laxil.
tr
6.2.1 []onrOnvnry, and Sr,,norrvrrr"
6.31'ype nrethod ancl its signillcarrcc
6.3.I Ditl'ercnt kinds o1'tvpes irt tlcsu'iptivc
Ir.r.rorror.r]-r
I
7. Newer trends in svstematics
7.1 Cherno and
7.2
C
serotaxot'loll\
Hr'
.
ytotaxononty
7 -l Nunrcrical ta\ol.ront)
1.4
(.'
ladistics
7.5. Molecular systematics
7.6 DNA bar coding y.r traditional taxononrv
3llr
8. Ethics in taxonomv
8.
I etlrics
rclirtecl to c()llections
tJ.l.l crcilit
8.I
8.
1
.l lcncling uncl borrort,ing
.l I-oan ot' rnatel'ietl
ol'sprccintcrrs
ti.l .1 c.re hitrrgc ot'ntutcriels
0
li.l.)
tJ.
I
.6
c:trllahttratitltl tttlcl C()-()llCl'atitltt tvith co-vlot'l"Ct's
Ltse
r)l' iarlguagu
2 Hr
.Ethics t.clatecl to Iatrlrrtlnric prrhlicati0tts
I "\ttthorshill tl1' til1ottott'tlc
li. l. I (' ot't'cs1tt)llrlcllcc
tt.l,i Strppressiotr tl l' clata
tt
l.
lrilpcl-\
ti.2.4 [ ]nclesilatrle f-eatttres cif tetxt':rlrottlic papers
8.3 tarorttltnists and usel' colrlttrttt-ttttes
{
9. -l'axonimic impctliments
I-lr
I rrlpeclulents to build urp LrIxot'toltric ctlllections arnd maintenance
c)
9.2 Shortage of nlan Power
9.3 lacl< of flndirrg tor taxonomic research
9.4 lacl< ttl'tt'airtirlg itl. taxt>tlottrr
c).-i
l.acli
o1'
l.ibrtrrr fircilitics
9 6 Intpretlitlletlts itt
1-ltltrl
ishills til\()lr()lllic rvtlrk
t).7 Soltrtions trt rll,erctltltc
I Internatitlllal ctl-ollerattotl
9.7
)
()-7
tlic irrlllcclitltcllts
[)er e loprllcrlt o[' lltxtltttrtttie cclll'l'cs
9 8 Neccl fire el'tlciept intcplitti6nal netu,'tlt'king
9
Linit
9 lhe desired enc'l Prtlcittct
I
.
7hr
Natural Selectirln:
l. iVlecharisnr ol-rrtrtur.al sclcction - rlirectional. clisruptive
2.
Natural selegtitlrl irl Islarids.
_') .
Serr-ral selection: llttrasexr,tal ancl illtersexLlal
feffblgt
h e.s r .s-
go
cr
tl
se tl e s lt I
1'rt
r
ancl start'rilizirlg selection
selectitltl-
-Sexy
t h c s i s'
tinitl.'t'heNlechanisms'
l0hr'
1.
pop.latiurr geneticrs populations. gene pool. gel're trequency: l-{ardr'-weinberg law"
l
il'l sl]ccttttrolt'
fir,ricler pr.ipcipie. lrottlerrccli c1'fcct and genetic cirifj as fhctors
speciationIsolatirrg ,rechapisprs- l'r't,:t,!ttrit' and ['o.t'iz-t'grttic' i's'oltttirtg ntat'htrni'\'t't1'\"
arll.putr-ic-1-lcr-ipar-tr.ic-1'Lrnr1-lutric-hcteropLttt-lc-
a
J
s\nlptttl'ic specizttitln-cc()t\pes'
('otrrrergent (iltlrlltlplast') -clivergetltC.-er.,olutio': Microe\i olirtion- i\,{acroerrolurtion.
;larallel cvoltttiotr.
il
r
[
i. 'l'empo of cr olution
;nit
b
(.
I
iraduulisin \,'s
,\
l{ lrr
;.rrtttcIrraLe
ti
c11LriIiLrrirnn
Anitgcnesis Vs ('laritrgcnesi:.
Lrnit 4. Molecular evolution
l0
:
hr
Neutral theorv r.tl'rnolccrrlilr e\ rritrtit)r'r: nr()icc:rrlrrr di\'cruence: nr()lcculltr clt'it'e.
I
clocks- -r]cncLie cclui.listartcc- ltuntun nritoclrortrlt'ial ntolccLrlat'clocl..
Phvlogr:netic relationships- Ilorrrologl'': IIt)nri)ltigoLrs scclr.rcnccs ot'pt'otcitts r-tncl [)Nr\
lVloIecr-rlarr
)
-
orthologours and pafalogoirs: parsinron\,aniil\sis: nucIcttticle serlLrcr]ec anallsis: DNA bar
codillg' l?r traclitional taxc)r'ron'r\
LJnit
5. Evolutinnary
.
L
1
'
.
trends
l0 hr
Biochenrical evolutir'x-r- Collapse of' Ortho-senesrs.
Stagcs in prirnate cvolutiorr inclucling llonrt): d11 ancl wct nosecl prinratcs. prosimians itnrl
sintiarrs-hunrans ancl
the Afiicirn apes - i\liicarr oriIin
fol
r.noilcrr.t hur-narts.
\'-
chromosorlal Adarn- mitochondrial [:r,e.
3.
Clonrnrunication. speech. language and sellawareness in printertes.
References:
.{.. Sr stcrttatics:
l.
David. lVI. l-{. ( raig Moritz and
L}art-rara
K.
N1.
1[t)t)6) Nlolecular S_tslenrutics. Sirtauer
Associates. lrrc.
2. David. lVI. S. (2009) t)NA lrarcoding u,ill 1'rcquentlr fhil in conrprlicatecl
groups: ani
cxanrple in wild potatrlcs. .Arrericart .lotrt'rtirl o1'l.Jotarrr ()(r((r). il171 I lt{9 1)orvnloacilltle
fionr
3.
w'ww.vcru.wisc.edu/spoonerlah/...,'Flar(lodes%r20anc19/o20w'ild9,,20
Kapotlr. V.C'(1998) Tlreory and practise o1'zrninrtrl taxorrorly. ()xtirrcl
Potatoes.pclf'
& IRI'l .Publi.. Co.
New t)elhi
jt.
Kipling. W. W: Brent. D.M. and Quenl.irr. D. W'. (1005)r['he I'}clils of'lJN;\ Barcoding
'Iaxtlnonr\. .Sls'/ l]ittl.
,351.1)t,urtloacla['rle ll'ont
and tlrc Need tilr lntcgrettive
-i4(-5):ti-t4
.t'i'.r'/rir,r txf
5.
N4ert'r'.
rtrdjottrnul\ o/'rt t'gi t't'1tritlt )-l
j
,\JJ 1xl,/
l. (l()$c)) Princiltlcs o1'Srstellatic ZoolciLt\ N4c(iravr tlill []o.rl. ('arupnr.
Irrc..
Ncw Yorl..
6.
7.
Narenclrarr.'I'.('(200ti)An irrtroductiort to laronirnr' . /trtllogicitl srn'\'c\ ()l'Inr'lia.
Stteath
P.ll.
i\. i97l:
Nurntcriclrl larorrrrnr\. l he l'r'inci1-'''lc: ltrtd
( lassrilcatiott.W H l rc'cruirrr & ( o.
l'r'ue
tiut' ol \rrnre rielrl
I'-r'olrltiolt
I
tttiti ,\llctt. ().1I il(t04t S;leciatiptr. Siltatret'Asseciltes Ittc - MlssatchLlsetts-
( 'rrr, nc.
[,s.,\
). I)arid.
I\'1. t-I.
Craig Moritz and fJtrrhara K. N{. (1996) Molecular Svsternatics.
Sinar-rer'
Associates. Inc.
3.
David. M. S. (2009) DNA barcoding will frequently fail in complicated groups: an
cxanrple in wild potatoes. Arrerican .f ournal o1'Botany' 96(6): 1117 I l89.Downloadable
tl'orr \\ \\ \\'. \'crll. w isc.eclLr,,slloorrcrla b,'.../BarClodes0z62()and?u20 W ild')i,20 Potatcles.pcll+. (ioLrltl. S .l 1 I t)t)7 ) Ontoucnr & l)hylogenr'. []ell<r'ap press. Harwar Universit\,
L'anr[rrirl-r.re.
5. Kiplins. Si
arncl
W'. Rrcrrt.
tlie Neecl ior tntesrative
rr'.sbirr rxfttrd journul,
6.
I).Nl
,,,*
trncl (Juerrtin.
'l'arononr\,.
c',qi t't'ltrittt
-['lrc
l)crils o1'DNA Barcoding
D. W. (200-s)
.Si,,r'/.
lliol
5l 5', 11 ltcl/
Mcl Ic'nr\. I-l.l\4. (2009) "HLulAr-r Evoluticlr".
l:vttltrtitttt' '['he lir,st f:'rtttt' Billion
54(5):tt44 tl5l.[)orvrtlozrdable tiot-tt
)'cur'.s'.
in
N4ichael Ruse
&. .loseph T'ravis.
'l'he Belkrtap Press
Canrhridse. I\4assaclruselts:
of Harvard Ljniversity' Press. p. 16-5
l.
Motoo Kirnura (1983,1 T'he neutral theor-v oI nrolecular evolution. ('eirttbriclge I-]riir,crsit-'-
Pt'ess.
t{.
Rqdgf_Et
,
! f4Jagc ancl EdgU!-I-_H.
(2000) Molecular Evolutiorr:
A
Phvlogenetic
Approach: Blacl<well science.
Stril<berger'. lVl
\\'. (100-5) l:r olution.
.loncs and Rartett Putrlishers. l.onilort
I' I{
A
C't'I C'A
I ,S
'/,o t('P 0l- BIocHF.MIS'l'RY
t. ,\etLurl lrciclitv antl titrirhlc aciclitr r,l'it stt'<'rntt ltttc[ lt wcali acid.
2. ('onr1-'larisr-rn of the burlfcrius capacities of tu'o buffers of'sanre pl-l
1
-). Qr"ral itati'n'e tests fbr carrbohr,'dt'ates
a) Qr-ralitative tests firr nror-rosaccharides (Crlr-rcose and fi'uctosc)
[-', ) QLralitatir c tcsts lirr d isaccharic]es (l.actosc. Vlaltosc & SLIcrosc
c i (lrralitatir e tcst: lirr polr sacchirricles (Dertrin & Starch't
d t lcientrtlcattitrn ol' rutl\lt()\\lr car'trohr,tlrtttcs ((llLrcrtse. l;t'rtulosc. l-actt'lsc. Vliiltosc.
\ucrose. Dextrin & Starch) lrr suitable tests.
)
4.
5
Qr-rantrtati ve estintation o l' carboh1'drettes
l.l.
Ustirnation til'bloocl qlueose
I.2.
l-oludine nrethocl)
E:stintatiolt ol'total
L-rr
carLrohvclrerte
colorimetric r-nethocl (Son-rrrgr-Nelsort rneth.odl O-
br
phenol-sr-rlphr-rric atcic[ nrethoc]
Qual itativ'c tc'sts lirr' lrrotcins
'i.tscin. I)eptoncs
il ) ('oloLrr reacti,,,ns u ith prote irrs (.Altrrrnrin- (
&
gcltttirr
)
[-,r i)r'cciltitutr()ll leileiirlr: rrith ltlotcins t.tlbtrrttirr. ('ascin. Pcpttltlcs & gclatirll
e ) lclcntrljcatitrn ol rrnIt.lt)\\n l]r'()tcin t,\l[.,ttntin. ( ase itl. I'c1-ltotlcs tL llclatirl)
rl
6.
1.
Qualitative tests fbr non-protein nitrogenous substances (urea. uric arcici and cl'eatilrine)
lderrtillcution of' urrl..norl,1 g3l'holrr,'clrates. protcrn itticl n()n-protein nitl'ogcnotts sttbstallccs
fl'onr ir grvcn solLrtirrn.
8.
Qr-rantrtutive cstilrati()n ol 1'lrotcins
a) E:stimation of'proteins by Bir-rret nrethod
b)
lsolation of'casein fiont co\^ s rrilli
9. Qr-rantitati ve estintertion cl f' non-proteiu nitrogen()Lls su bsturtces
a) Quarrtitatitlrr ul blood u,-e a br diacct', I rr-touortnci ttrcthod
bt Deterrninatit-ru of urrine creatine !lr, alkaline picrate method
10. Quantitative estirnation of lipids
a) l-:stirnation of total serLnn chtllcstcroI hr /.ttl;' s nrethtlcl
ht Saportiticirtion rirrrlhcr ol'oils c()c()nrrt tril & srounri ttut oil.
c ) lorlinc nLlnrtrcr trt'lirls
References:
L
2.
3.
4.
.Iata
Plunrnrer David. T.(......) Arr introductiou' to practieal biocllenristn
Mc Cra\,vHill. New Delhi
Oser. U.L. (1965) I-[au,l<'s Phvsit-rlogicarl Biochernistrv. McGrar.r, FIill Book Co.
Sadasi\Lln. S. erncl \4anicl<anr. A.. (200-i). []iochentical rrethttcls- \icu ,{ge lutcrnutionalNer,r l)clhi.
Keith Wilson and.lohrr Walker'(2008). Principle.s ancl teclrrric;ues of'Bioclrentistn ancl Molecular'
biolog,"-
5
-
(r'l' edn. Carrbriclge Urriversitv Press
.litt,ttt'r.rnlan.
.1.(
) I.ltboratt)r', ,'ilanLral in Ilioe lrcrnistrr. W'ile r Ij:ustcrn l-td.
,e-
.ZOICI>02-lliollhvsics, lliostatistics anrl
St,s t/tn at ics
B iop hys ics
I pll nretcr untl ntcnsLtrcntcnt ol pl
I
2. Paper cht'ontatouraplir ol'antirtr', ucicls. nrirtrrres. icicntitlcati()n of Lrnk111r\\n .rntirrt', aLe icls and
s
Llgars.
llltratiotr chrotlatographl (Scparatic)rr of sturch lionr slucose)
'l'lrin
-1.
-3 Cel
laver chron'r:rto_r{raphr tll'ernrino acids anrl sLlgars.
-5 Serunt elce [r'ophoresis.
7
l)ertL'rlttinatiotr tl1 at sorption coct'tlcicnt i'urtl concenttlrtion ol'trr-rl<norvr-r strlrrtiorrs l'lr,calihratiorr
cLu'\'c rrsing .r crrlr)Lu'cd soIrr1ion.
8. Ahsclr-Ption s[]cctnlnt ol'u eolrrrrrecl strlLrtion (K\ln().)
c).
[)r'awings Lrsinu cuntcru luciclir
lliostatistics
l. Preparation o1'treclLrenc\ tahlc rr rrh gir en tlatrr
] [)iirgrittltiltltlit' l)i'est'rlllttitrlt ,rl rr rtsu> tl,ttlr lil i',elrltr t!r tlru ltrltr ol
[-,.rr
.ltirlnrnt: luttl
lrte
rliitgt'urls.
l-+
,
,
a.
a
:,. ( I raphic i'lt'cscl.'ttattot't
of hist()gl'l'lllr'
()l p()ptll111 ilrtr Ji:triillititlt't irr thc lilt'nr
fi'eq ttenc,v Ptll
Y
goll
aricl ircclLlcllc\ ctlr\/c
(.tlnr1'rlrtitti()ll
-1.
()
elis;telsit-ltlttlttht't)pt)l11ctl'lcciatllol'schotllchildrerl'
i' t-t-tcl-isttt'cS tt l' e ctltt'nl
of l-rinorlial ancl poisolt clistribr-rtions
i, the u'ive,sity cilllrpLts
nur,ber orchird'cn pr'r ['an]ily
(r. Estimatio,.,.f
'rcarr
populatiotl of platlklotrs
of
7. E.stimation
t;-pes of
oict'flc^c'clf a ter'r'cliets orl dif'terent
c()lrllal'rs(),
thc
rir'
experinre.t
g.
5.
si,ulatitl'
Desig.i,u.l-ir.
atr i nral
s
[-r-lr
N()V
11',t r-rlethtlc] o t' A
A'
Resressi.. a.irr'sis ancl c.rrelati..
q
a.aly'sis
.t-a
of a grotrp of
data tlf treights attcl weight
sludcnts
10. Data attalr'sis bY SPSS'
Syttfrmatics
I . c 0I
lcctr.r'r.
P
rc:serr ati
t-r
tt atrcl cr'trati tltr
tl1' spectlllel1S
up
Irishcs'itlscctsritttt) otlter)
lclentitlcution o1' attit.l]itls
(
L
nt in
3.
illl Lllll 1 5 sPec tlllcll
s
(sinlplc: brircket)
Pteparattitltl o{- dicltototlrtlrts
to thnrilvi
getrcric
s1'lccies levcl-
thcl iclcrrtillctl
liel,s trlitrilrrlttrl tt:t-t.st:rs l.rtlt-tl
specinrens.
Evolution
'l
cvt-rltttitrtr l' I .rcrcises irl tli"'ergs11[
. l-.rercises ill c()11\cl'gclll
Refercncc
jtthu I t l(tt)l )
sr;ol trtltltr'
biologicirl
, .. .r,, r
11'1)l1l lcntal arnrl
l'r'actical strttistics lirt' ctrl
sctclrtrsLs
itllirl
rr
ilct itttcl :trtls'
Fly UP