Science at the heart of medicine Jeffrey E. Segall, Ph.D.
Science at the heart of medicine Jeffrey E. Segall, Ph.D. Professor, Anatomy and Structural Biology Betty and Sheldon Feinberg Senior Faculty Scholar in Cancer Research Dr. Segall received his original research training in biophysics and the analysis of bacterial chemotaxis (movement directed by extracellular gradients of chemicals) at the California Institute of Technology. He then performed postdoctoral research at the Max Planck Institute for Biochemistry in Germany on chemotaxis of the cellular slime mold Dictyostelium discoideum. Upon becoming a member of the faculty at Einstein, Dr. Segall continued to study the mechanisms of eukaryotic chemotaxis, and extended his research to the analysis of yeast polarization and tumor cell metastasis. His current research focuses on the mechanisms of tumor cell invasion and metastasis, with an emphasis on how growth-factor receptors contribute to these processes. He has made important contributions to the study of tumor cell motility in vivo, including intravital imaging of breast cancer invasion in the primary tumor and demonstrations that growth-factor receptors can enhance metastatic ability independent of growth. Dr. Segall is the author of more than 80 scientific papers on cell and cancer biology. He has served on study sections for the Department of Defense Breast Cancer Research Program, the American Cancer Society and the National Institutes of Health. He is currently in the tumor microenvironment study section. Dr. Segall has chaired Gordon Research Conferences on gradient sensing and directed cell migration, and on sensory transduction in microorganisms. Office of Communications & Public Affairs, Jack and Pearl Resnick Campus, 1300 Morris Park Avenue, Bronx, NY 10461